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In this study, state-of-the-art assemblers were used to generate different sets of contigs for bacterial genomes. We have developed and built a Contig Integrator for Sequence Assembly (CISA) to integrate the sets of contigs from different assemblers, and have evaluated the quality of our integrated assembly. Compared with the assemblies generated by each individual assembler and assembly integrator, the hybrid assembly integrated by CISA exhibits superior contiguity and accuracy. |
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In this study, state-of-the-art assemblers were used to generate different sets of contigs for bacterial genomes. We have developed and built a Contig Integrator for Sequence Assembly (CISA) to integrate the sets of contigs from different assemblers, and have evaluated the quality of our integrated assembly. Compared with the assemblies generated by each individual assembler and assembly integrator, the hybrid assembly integrated by CISA exhibits superior contiguity and accuracy. |
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'''This work has been published in [http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0060843 PlOS ONE].'''
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'''This work has been published in [http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0060843 PLoS ONE].'''
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= A schematic overview of CISA = |
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= A schematic overview of CISA = |
