Manual @Mar 7, 2011 5:38:55 PM

Reconstruction

  • Model importing and editing

Right click on Model databases, you can import a metabolic model in SBML/spreadsheet format as described in Metabolic Models.

You can directly edit/update the content of the imported model.

  • Reference database creation

Right click on Reference databases, you can import a reference database provided in Reference Databases to create your own reference database.

You can add the information about metabolites and reactions described in your model to the reference database by right clicking on a model.

  • Draft reconstruction generation

A draft reconstruction can be generated by mapping a blank model outputed by GBKPaser, only containing gene informaiton, to a reference reconstruction. tically extract reactions whose associated orthologous genes can be mapped to a reference reconstruction . Such an automatic function can greatly reduces the manually typing effort and provides accurate evaluations on Boolean statement once the list of orthologous-gene pairs is available.

Reference database creation

Right click on the Project to Creat/Edit Models, Reconstruction

  • Simulation
  • Visualization