Paper:
Reducing assembly complexity of microbial genomes with single-molecule sequencing
Data:
http://www.cbcb.umd.edu/software/PBcR/closure/index.html
目前驗證結果:
1 filtered_short_read(100X or 118X) 校正效果較好 => Hybrid assembly to do list (3) 2 pacbioToCA 搭配genome size 會得到較正常的 coverage depth(比pacbioToCA自已估算好) => 20130718_驗證Hybrid_assembly那篇paper的結果 3 filtered_long_read(25X) 組裝效果較好 => Hybrid assembly to do list (2) 4 NHRI_Patching => 用25X的corrected_clr, 效果沒有比較好(沒有比用所有的corrected_clr好)。