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| We have used <span style="color:#FF0000;background-color:#ffffcc;">ALLPATHS-LG</span> to assemble three bacterial genomes: [[E. coli]], [[R. sphaeroides]], and [[S. pneumoniae]]. The sequencing reads for these three genome assemblies are summarized in the following table (<span style="color:#FF0000;background-color:#ffffcc;">D1-D3</span>). | We have used <span style="color:#FF0000;background-color:#ffffcc;">ALLPATHS-LG</span> to assemble three bacterial genomes: [[E. coli]], [[R. sphaeroides]], and [[S. pneumoniae]]. The sequencing reads for these three genome assemblies are summarized in the following table (<span style="color:#FF0000;background-color:#ffffcc;">D1-D3</span>). | ||
| - | We have conduct a <span style="color:blue;">hybrid approach</span> proposed by Koren ''et al.''([[http://www.ncbi.nlm.nih.gov/pubmed/22750884 ref]]) to correct long reads (<span style="color:blue;">D5</span>) with short reads (<span style="color:blue;">D4</span>) (by [http://sourceforge.net/apps/mediawiki/wgs-assembler/index.php?title=PacBioToCA PacBioToCA]), then to ''de novo'' assemble the corrected long reads (by [http://sourceforge.net/apps/mediawiki/wgs-assembler/index.php?title=runCA runCA]) for ''E. coli'' genome reconstruction. | + | We have conduct a <span style="color:blue;">hybrid approach</span> proposed by Koren ''et al.''([http://www.ncbi.nlm.nih.gov/pubmed/22750884 ref]) to correct long reads (<span style="color:blue;">D5</span>) with short reads (<span style="color:blue;">D4</span>) (by [http://sourceforge.net/apps/mediawiki/wgs-assembler/index.php?title=PacBioToCA PacBioToCA]), then to ''de novo'' assemble the corrected long reads (by [http://sourceforge.net/apps/mediawiki/wgs-assembler/index.php?title=runCA runCA]) for ''E. coli'' genome reconstruction. |
| {| {{table}} border="1" | {| {{table}} border="1" | ||